Honduras has a high incidence of cervical cancer linked to infection with one or more high risk human papilloma virus (HPV) types, coupled without the necessary resources for effective cancer screening. The detection of HPV has become increasingly important in cervical cancer screening and the treatment of cancer precursors. Furthermore, significant differences in the oncogenicity of HPV genotypes have been noted, and the distribution of these genotypes varies geographically. Notably, our lab has demonstrated that the most common high risk HPV genotypes detected from cervical cancer screenings differed from those routinely found in the United States. 1 This study aims to build on this analysis by investigating the prevalence and distribution of HPV genotypes of cervical cancer tumor tissues in Honduras. As the causative agent of cervical cancer, detection of high risk HPV types has the potential to improve health outcomes relative to the less sensitive visual and cytological tests.
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